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Decoding the architecture of life to design future biosystems
I am Taner Karagöl, a medical doctor, researcher, and inventor dedicated to decoding the architecture of life to solve critical challenges in human disease.
My work spans structural biology, protein engineering, and genomics, alongside clinical research, connecting molecular mechanisms to patient outcomes.
I will be joining MIT as a Postdoctoral Fellow. I conduct research with the Massachusetts Institute of Technology (MIT) and University College London. I am a medical doctor, with previous clinical placements at Harvard Medical School and King's College London.
You can find more detailed information here:
Other links:
Research areas
Macromolecule Structure
& Design
-Protein Engineering: Design of environmental variants and inhibitory isoforms. -Structure-Based Drug Design: 3D structure predictions, MMGBSA, MMPBSA, and binding predictions. -Membrane Biophysics: MD simulations of lipid-protein conformational dynamics. -Oligomers & Lipid Interactions: Modeling neuronal assemblies and membrane distortions.
Featured Article:
Genomics
& Molecular Evolution
-Clinical Genomics: Locus-specific variant databases (Haemophilia, Glutamate). -Evolutionary Medicine: Purifying selection and Shannon entropy modeling. -Mutational Profiling: Analysis of V>A>T pathways and genetic code architecture. -Transcriptomics: Ancient RNA conservation and splice-altering variations.
Featured Article:
Clinical &
Translational
- Neuroscience & Immunology: Disease-involved proteins and immune response pathways. -Statistical Medicine & AI: Open science automation workflows, AI models. -Software & Tool Development: Creation of toolkit and bioinformatics pipelines. -Theoretical Biology: Models to predict biological competition.
Featured Article:
Life & Science
Conference Talk, Swiss
Medical Rotations, Harvard
In the Lab
Travel
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