welcome!
I am Taner Karagöl, a researcher deeply fascinated by biological macromolecules for their critical roles in human disease and molecular evolution.
Based in Istanbul and London, I aim to bridge the disciplines of structural biology, neuroscience, immunology, artificial intelligence, bioinformatics and other fields of biomedical research to advance our understanding of molecular mechanisms and develop innovative therapeutic approaches.
I currently work as an intern Doctor med. (pre-registered physician) at Istanbul University Hospital. I conduct structural research under the guidance of Shuguang Zhang at MIT and participate a genomic research collab with the Royal Free Hospital London / UCL Medical School (Steven J Perkins - Darwin Building UCL).
You can find more detailed information here:
Other links:
research areas
Protein Structure / Function
- MD simulations for membrane proteins, lipid distortions - MMGBSA, MMPBSA, and SVM predictions of binding affinity - Neuronal proteins, their oligomers and dimers - Lipid compositions related to olfactory neurons - Water-soluble QTY-variants of membrane proteins, neuronal proteins
Featured Article:
Genomics and Genetics
- Clinical variant databases, their design and maintenance - mRNA alterations, ancient RNAs, RNA conservation - Heamophilia Variants FIX, FVIII, Glutamate transporter gene architecture and splice altering variations
Featured Article:
Medicine
- Neuroscience, Disease evolution, Immunology, Clinical variant databases
Featured Article:
Drug Design
- Inhibitory isoforms of transporters and membrane proteins -Isoform-based Tau-like self-assemblies
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Evolutionary Biology
- Evolutionary residue analysis - Partial Spearman correlations and statistical modeling - Kernel causality and confounding variable partial correlations - Puryfiying selection, Shannon entropy, and evolutionary models - Genetic code structure and mutational pathways (e.g., V>A>T mutations) - Evolutionary Game Theory - Modeling evolutionary nodes in R
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Other
- AI, Open science - MD simulations - Bioinformatics tools
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fun pics
London, UK
London, UK
Germany
Medical
London, UK
Cologne, Germany