Taner Karagöl

welcome!

I am Taner Karagöl, a researcher deeply fascinated by biological macromolecules for their critical roles in human disease and molecular events.

I aim to bridge the disciplines of structural biology, neuroscience, immunology, artificial intelligence, bioinformatics and other fields of biomedical research to advance our understanding of molecular mechanisms and develop innovative therapeutic approaches.

I currently study as an intern Doctor med. (last year med student) at Istanbul University Hospital. I conduct structural research with Shuguang Zhang at Massachusetts Institute of Technology (MIT) and participate a genomic research collab with UCL Medical School (Steven J Perkins - Darwin Building UCL).

You can find more detailed information here:

About me

research areas

Protein Structure / Function

- MD simulations for membrane proteins, lipid distortions - MMGBSA, MMPBSA, and SVM predictions of binding affinity - Neuronal proteins, their oligomers and dimers - Lipid compositions related to olfactory neurons - Water-soluble QTY-variants of membrane proteins, neuronal proteins

Featured Article:

Karagöl et al, 2024a

Genomics and Genetics

- Clinical variant databases, their design and maintenance - mRNA alterations, ancient RNAs, RNA conservation - Heamophilia Variants FIX, FVIII, Glutamate transporter gene architecture and splice altering variations

Featured Article:

Karagöl et al, 2024c

Medicine

- Neuroscience, Disease evolution, Immunology, Clinical variant databases

Featured Article:

Karagöl et al, 2024b

Drug Design

- Inhibitory isoforms of transporters and membrane proteins -Isoform-based Tau-like self-assemblies

Featured Article:

Karagöl et al, 2024d

Molecular Biology

- Residue analysis - Partial Spearman correlations and statistical modeling - Kernel causality and confounding variable partial correlations - Puryfiying selection, Shannon entropy, and evolutionary models - Genetic code structure and mutational pathways (e.g., V>A>T mutations) - Game Theory

Featured Article:

Karagöl et al, 2025a